Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TGFBR2 All Species: 44.55
Human Site: Y424 Identified Species: 89.09
UniProt: P37173 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P37173 NP_001020018.1 567 64568 Y424 G Q V G T A R Y M A P E V L E
Chimpanzee Pan troglodytes XP_001166587 603 68631 Y460 G Q V G T A R Y M A P E V L E
Rhesus Macaque Macaca mulatta XP_001095987 567 64487 Y424 G Q V G T A R Y M A P E V L E
Dog Lupus familis XP_534237 569 64614 Y426 G Q V G T A R Y M A P E V L E
Cat Felis silvestris
Mouse Mus musculus Q62312 592 67103 Y449 G Q V G T A R Y M A P E V L E
Rat Rattus norvegicus P38438 567 64223 Y424 G Q V G T A R Y M A P E V L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508269 597 68110 Y454 G Q V G T A R Y M A P E V L E
Chicken Gallus gallus Q90999 557 63290 Y414 G Q V G T A R Y M A P E V L E
Frog Xenopus laevis P27041 511 57917 L369 R Y M A P E V L E G A I N F Q
Zebra Danio Brachydanio rerio NP_878275 556 63419 Y410 G Q V G T A R Y M A P E V L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P50488 744 84391 Y483 G Q V G T K R Y M S P E M L E
Sea Urchin Strong. purpuratus XP_001184520 615 68501 Y449 G Q V G T P R Y M S P E A L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94 98.9 89.4 N.A. 88.1 91.5 N.A. 74.5 74.9 34 66.8 N.A. N.A. N.A. 25.1 32.3
Protein Similarity: 100 94 99.6 93.5 N.A. 92.9 96.3 N.A. 82 85.1 51.6 79.8 N.A. N.A. N.A. 42.2 49.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 100 N.A. N.A. N.A. 80 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 13.3 100 N.A. N.A. N.A. 93.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 75 0 0 0 75 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 9 0 0 9 0 0 92 0 0 92 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 92 0 0 92 0 0 0 0 0 9 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 9 0 0 0 0 0 92 0 % L
% Met: 0 0 9 0 0 0 0 0 92 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 9 9 0 0 0 0 92 0 0 0 0 % P
% Gln: 0 92 0 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 9 0 0 0 0 0 92 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % S
% Thr: 0 0 0 0 92 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 92 0 0 0 9 0 0 0 0 0 75 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 92 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _